Targeting Emotion Dysregulation to Reduce Suicide in People with Psychosis

Not Applicable

Recruiting

• Conditions: Suicide; Psychosis
• Interventions: Behavioral: Dialectical Behavior Therapy Skills Training

• Registration Number: NCT05440214
• Lead Sponsor: University of Maryland, Baltimore

Brief Summary

People with psychotic disorders are excluded from most suicide-focused clinical trials despite incredibly high rates of completed suicide, and interventions that have been tested for this population have shown limited impact on suicide. Emotion dysregulation is a significant suicidogenic factor that is understudied in people with psychotic disorders. The investigators propose to implement and evaluate an intervention targeting emotion dysregulation in people with psychotic disorders while employing rigorous statistical modeling and measurement techniques including Ecological Momentary Assessment, which will support future advanced research on suicide and suicide prevention for this high-risk group.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-06-27
• Study First Submitted QC: 2022-06-27
• Study First Posted: 2022-06-30
• Study Start: 2022-12-02
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-22
• Last Update Posted: 2024-11-26
• Primary Completion: 2025-09-01
• Study Completion: 2026-06-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• At least 18 years old
• Psychosis spectrum disorder as assessed by the Mini International Neuropsychiatric Interview (MINI) for Psychotic Disorder Studies
• Heightened suicide risk as determined by a score of 8+ on the Suicide Behaviors Questionnaire-Revised (SBQ-R). This cutoff may be revised downwards (toward lower suicide risk) if recruitment appears difficult, but will not be revised upwards.
• Enrollment and engagement in outpatient mental health services with at least one mental health service in the previous month
• 6+ grade equivalent reading level as assessed by the Wide Range Achievement Test 4 (WRAT-4)

Exclusion Criteria

• Chart diagnosis of intellectual disability (DSM5 317, 318), traumatic brain injury, or deafness.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Dialectical Behavior Therapy - Skill Training	Dialectical Behavior Therapy Skills Training	-

Primary Outcome Measures

Name	Time	Method
Emotion Dysregulation	Four months	Difficulties in Emotion Regulation Scale (DERS-36). Minimum score: 36. Maximum score: 180. Higher scores are worse.
Suicidal Ideation	Four months	Beck Scale for Suicide Ideation. Minimum score: 0. Maximum score: 42. Higher scores are worse.

Trial Locations

Locations (1)

University of Maryland; 🇺🇸 Baltimore, Maryland, United States