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临床试验/NCT03907345
NCT03907345已完成不适用

Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure

Ruhr University of Bochum2 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2019年6月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
2
主要终点
Behavioral Approach Test (BAT) for Spiders

研究概览

简要总结

This study investigates whether a one-session exposure treatment for spider-related stimuli can lead to a generalization of extinguished fear to height-related stimuli in individuals with comorbid fear of spiders and fear of heights.

详细描述

Exposure therapy has been proven to be effective in the treatment of specific phobias and in a variety of fear evoking situations and stimuli. However, since there is a high prevalence of comorbid fears, therapeutic interventions can get very extensive when each fearful situation and / or stimuli needs to be treated separately and over a repeated number of times. It has recently been shown, that exposure to one fearful stimuli (i.e., a spider), can also lead to a reduction of fear to another, perceptually and conceptually related, but untreated fearful stimulus (i.e., a cockroach) (Preusser, Margraf & Zlomuzica, 2017). Potentially, this generalization of exposure effects might also be relevant for coexisting fears that do not share conceptually related fearful stimuli (e.g., fear of spiders and fear of heights). The present study aims to investigate whether successful exposure treatment to one fearful stimulus (i.e., a spider) can also lead to a reduction of fear to an untreated fear evoking stimulus (i.e., height).

Participants will be randomly assigned to the treatment or no-treatment condition. The entire experimental procedure will take place in three sessions. The first session incorporates spider and height fear related questionnaires and two Behavioral Approach Tests (BATs): One that involves a spider and one that involves height. These BATs are counterbalanced in each group with half of participants receiving the spider BAT first and the height BAT second, and vice versa. The second session takes place approximately seven days later. The treatment group receives a seven-step in vivo exposure with spiders (duration: 1,5 hours). Twenty-four hours later, session 3 takes place and involves the same measures that were applied in session 1. The treatment and no-treatment group receive an identical set of measures except that the no-treatment group will not be subjected to exposure. The effects of exposure-based anxiety reductions toward spiders (treated fear stimulus) and heights (untreated fear stimulus to assess generalization of treatment outcome) are assessed on the behavioral and subjective level at pretreatment and posttreatment (24 hours after exposure).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Comorbid presence of fear of spiders and fear of heights [Potential diagnosis of specific phobias (arachnophobia and acrophobia) assessed by application of the Diagnostic Short-Interview for Mental Disorders (Mini-Dips)].

排除标准

  • Any acute or chronic mental and / or somatic disease
  • Psychological, psychiatric, neurological or pharmacological treatment (Application of the Mini-DIPS to screen for the presence of a psychological condition)
  • Drug or alcohol abuse
  • Pregnancy

结局指标

主要结局

Behavioral Approach Test (BAT) for Spiders

时间窗: Change in BAT scores from pre- to posttreatment (across one week from pretreatment to posttreatment)

Change in the Behavioral Approach Test (BAT) with spiders (treated fear stimulus) \[Time Frame: Pretreatment (approx. 1 week before the treatment), Posttreatment (1 day after treatment), Follow-up (4 weeks between treatment and follow-up)\]. During the Behavioral Approach Test (BAT) the closest distance to a spider as well as subjective fear and heart rate is measured.

Behavioral Approach Test (BAT) for Heights

时间窗: Change in BAT scores from pre- to posttreatment (across one week from pretreatment to posttreatment)

Change in the Behavioral Approach Test with heights (untreated fear stimulus) \[Time Frame: Pretreatment (approx. 1 week before the treatment), Posttreatment (1 day after treatment), Follow-up (4 weeks between treatment and follow-up)\]. During the Behavioral Approach Test (BAT) the level of the approached height as well as subjective fear and heart rate is measured.

次要结局

  • Fear of Spiders Questionnaire (FSQ)(Change in FSQ scores from pre- to posttreatment (across one week from pretreatment to posttreatment))
  • Acrophobia Questionnaire (AQ)(Change in AQ scores from pre- to posttreatment (across one week from pretreatment to posttreatment))
  • Spider Beliefs Questionnaire (SBQ)(Change in SBQ scores from pre- to posttreatment (across one week from pretreatment to posttreatment))
  • Spider Fear Questionnaire (SPQ)(Change in SPQ scores from pre- to posttreatment (across one week from pretreatment to posttreatment))

研究者

发起方
Ruhr University of Bochum
申办方类型
Other
责任方
Principal Investigator
主要研究者

Armin Zlomuzica

Principal Investigator

Ruhr University of Bochum

研究点 (2)

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