EUmetriosis: Insights Into the Pathogenesis of Endometriosis
Not Applicable
Recruiting
- Conditions
- Endometriosis
- Registration Number
- NCT07000786
- Lead Sponsor
- Université Catholique de Louvain
- Brief Summary
This study investigates epigenetic changes in menstrual effluent and plasma from women with endometriosis to identify potential non-invasive diagnostic biomarkers for the disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
- Premenopausal
- In spontaneous menstrual cycle (no hormonal treatments for the last 3 months)
- Healthy or with a clear diagnosis of endometriosis via ultrasound, MRI or laparoscopy
Exclusion Criteria
- HIV or Hepatitis positive
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Epigenetic analysis Throughout the entire study, approximately during 3,5 years miRNA
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What epigenetic biomarkers in menstrual effluent correlate with endometriosis severity and progression?
How do DNA methylation patterns in plasma from endometriosis patients compare to healthy controls in the EUmetriosis trial?
Are there specific histone modifications associated with endometriosis subtypes in menstrual tissue samples?
What non-invasive diagnostic tools are being developed for endometriosis based on epigenetic profiling?
How might findings from NCT07000786 influence the development of targeted therapies for endometriosis?
Trial Locations
- Locations (1)
Cliniques universitaires Saint-Luc
🇧🇪Brussels, Belgium
Cliniques universitaires Saint-Luc🇧🇪Brussels, BelgiumMarie-Madeleine Dolmans, MD, PhDPrincipal Investigator