TCTR20210826001已完成不适用
Reactogenicity and immunogenicity of mRNA COVID-19 vaccine (ComirnatyTM) among Thai adolescent with chronic diseases
Pediatric Infectious Disease Society of Thailand (PIDST)0 个研究点目标入组 300 人开始时间: 2021年8月26日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 300
研究概览
简要总结
Our findings show that adolescents with impaired immunity had a poor immune response after the 2-dose of BNT162b2 vaccination, and require an additional dose as recommended by the Advisory Committee on Immunization Practices. For adolescents with other chronic diseases, 2-dose of BNT162b provide high neutralizing antibody up to 3 to 6 m post vaccination. However, with the era of Omicron variants, with immune escape, a booster dose should also be considered.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 12 Years 至 18 Years（—）
- 性别
- All
入选标准
- •Adolescence between 12-18 years of age at the enrollment date
- •No history of COVID-19 vaccination
- •No history of COVID-19 infection
排除标准
- •Acute fever with body temperature above 37.8 degree Celsius within 3 days
- •History of drug anaphylaxis or vaccine ingredient allergy
- •History of lived vaccine administration within 4 weeks
研究者
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