The effect of postbiotic mouthwash on oral ulcerative lichen planus lesions
- Conditions
- oral lichen planus.Lichen planus
- Registration Number
- IRCT20240122060773N1
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Patients suffering from ulcerative or erosive oral lichen planus based on the diagnosis of an oral disease expert in the clinical view and its confirmation by an oral pathologist from the biopsied tissue.
Patients with pain higher than 2 on the visual analog scale during the initial clinical examination
Age range from 18 to 60 years at the time of signing the informed consent
At least one erosive mucosal tissue larger than 1 cm
Consent to participate in the study
Patients with gastrointestinal ulcers
Patients with uncontrollable and severe medical conditions
Patients with dementia, mental disorders or alcohol addiction
Pregnancy and breastfeeding
Patients who have a history of taking immunosuppressive drugs in the last 4 weeks.
Patients with dysplastic lesions
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intensity of pain. Timepoint: One week, two weeks and four weeks. Method of measurement: Visual Analogue Scale.;The size of oral ulcers. Timepoint: One week, two weeks and four weeks. Method of measurement: periodontal probe.;Recurrence rate. Timepoint: One week, two weeks and four weeks. Method of measurement: Therapist observation and patient report - periodontal probe and visual analog scale test.
- Secondary Outcome Measures
Name Time Method