Comparison of different medication protocols for induction of ovarian in the cycles of in vitro fertilization on expression of GREM 1, HAS2 and PGS2 genes as determinants of oocyte development

Phase 2

• Conditions: Condition 1: male infertility. Condition 2: Female infertility.; Male infertility; Female infertility, unspecified

• Registration Number: IRCT201201046541N2
• Lead Sponsor: Shiraz university of Medical Sciences, Infertility research center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

Infertility with male factor or with unexplained cause. Exclusion criteria: all the cases with known female factor.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of oocytes. Timepoint: At the time of Harvesting the oocytes. Method of measurement: Counting the oocytes.;Quality of oocytes. Timepoint: At the time of oocyte retrival. Method of measurement: based on quality grading(GV-MI-MII).;Embryo count. Timepoint: 3 days after oocyte retrival. Method of measurement: microscopic evaluation.;Evaluation of expression of HAS2 Gene. Timepoint: after oocyte retrival. Method of measurement: Polymerase Chain Reaction (PCR).;Quantity of GREM1 expression. Timepoint: at the time of oocyte retrival. Method of measurement: PCR test.;Evaluation of expression of PGS2 Gene. Timepoint: after oocyte retrival. Method of measurement: Polymerase Chain Reaction (PCR).