Evaluation of the effect of phenylephrine on spinal anesthesia induced hypotension in cesarean sectio
Phase 2
- Conditions
- spinal anesthesia induced hypotension.Other complications of spinal and epidural anaesthesia during labour and delivery
- Registration Number
- IRCT201601238768N4
- Lead Sponsor
- Vice chancellor for Research and Technology, Hamadan University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 120
Inclusion Criteria
All of the ASA 1 healthy term parturients referring to Fatemieh hospital candidate for Cesarean section were included in the study.
Exclusion criteria: chronic hypertension; pre eclampsia; twin pregnancy;, preterm labor; allergy to drugs; cardiovascular disease; renal disease and previous abdominal surgeries with adhesion band and fibrosis.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Spinal anesthesia induced blood pressure change. Timepoint: before performing spinal anesthesia, every 2 minutes until delivery and then every 5 minutes until the end of surgery. Method of measurement: blood pressure was measured with automatic blood pressure device and hypotension was defined as more than 20% decrease of BP compared to baseline.
- Secondary Outcome Measures
Name Time Method Heart rate. Timepoint: before performing spinal anesthesia and then every 5 minutes until the end of surgery. Method of measurement: Electrocardiogram monitoring.;Nausea. Timepoint: every 5 minutes until the end of surgery. Method of measurement: observation.;Vomiting. Timepoint: every 5 minutes until the end of surgery. Method of measurement: observation.;Rescue vasopressor dose. Timepoint: at the end of surgery. Method of measurement: measurement.;Neonatal condition. Timepoint: at min 1 and 5. Method of measurement: Apgar score mesurements by observation and physical examination.