To compare the efficacy of opioid free anaesthesia vs opioid anaesthesia in terms of post-op VAS score, hemodynamic stability, postoperative nausea and vomiting,and sedation score

Completed

• Conditions: Other Procedures,

• Registration Number: CTRI/2022/01/039288
• Lead Sponsor: hariharan

Brief Summary

INTRODUCTION

•Opioid free anesthesia in bariatric surgery has been shown to be associated with quicker recovery during the post operative period, shorter hospital stay with consequent reduction in health care cost, early ambulation of patients and minimization of side effects of opioids. Similar such benefits are being shown in other surgeries

• we compare the efficacy of opioid free anesthesia with conventional opioid based anesthesia for nasal surgeries.

PRIMARY OUTCOME is measureʉۢPostop Analgesic efficacy - Postopertive pain for 24 hours (VAS every 30 min for first 2 hours in PACU, then at 4,6,8,12,24 hours)

SECONDARY OUTCOME is to measure â€¢Intraoperative hemodynamics â€¢Intraoperative sevoflurane requirements to maintain adequate BIS (end tidal values) – data captured every 15 min â€¢Intraoperative bleeding in the surgical field â€¢PONV•Postop sedation

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-15
• Study Completion: 2022-10-07
• Last Update Posted: 2024-03-28

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1.Elective Nasal surgeries (septoplasty/ FESS) 2.Patient belonging to ASA class I and II.

Exclusion Criteria

• •Patients with ASA class III and IV •Patient with endorgan dysfunction •Hemodynamically unstable patients •Emergency cases •Pregnant and lactating women •Patients on α blocker and patients with HR <55/min.
• •Asthmatic patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postop Analgesic efficacy - Postopertive pain for 24 hours	Postop Analgesic efficacy - Postopertive pain for 24 hours

Secondary Outcome Measures

Name	Time	Method
1.Intraoperative hemodynamics	2.Intraoperative sevoflurane requirements to maintain adequate BIS (end tidal values) – data captured every 15 min

Trial Locations

Locations (1)

Sri ramachandra institute of higher education and research center; 🇮🇳 Kancheepuram, TAMIL NADU, India

Sri ramachandra institute of higher education and research center

🇮🇳Kancheepuram, TAMIL NADU, India

Dr hariharan

Principal investigator

9443371594

5594hariharanmbbs@gmail.com