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Clinical Trials/NCT01128309
NCT01128309
Completed
Not Applicable

Stress Reduction and Anxiety: Effects on the Function and Structure of the Brain

Massachusetts General Hospital1 site in 1 country29 target enrollmentMay 2010
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ConditionsGeneralized Anxiety Disorder

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Generalized Anxiety Disorder
Sponsor
Massachusetts General Hospital
Enrollment
29
Locations
1
Primary Endpoint
brain activation and structure as assessed by MRI
Status
Completed
Last Updated
13 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The aim of the study is to test whether Generalized Anxiety Disorder (GAD) patients that participate in a Stress Reduction Intervention show a brain activation pattern (assessed by MRI) indicative of improved emotion regulation compared to an active control intervention.

Registry
clinicaltrials.gov
Start Date
May 2010
End Date
April 2011
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Britta Holzel

Research Fellow

Massachusetts General Hospital

Eligibility Criteria

Inclusion Criteria

  • •participation in the study 'Stress Reduction Techniques and Anxiety: Therapeutic and Neuroendocrine Effects" by Dr. Elizabeth Hoge

Exclusion Criteria

  • •metallic implants
  • •left handed
  • •epileptic seizures
  • •head trauma
  • •weight over 350 pounds
  • •claustrophobia

Outcomes

Primary Outcomes

brain activation and structure as assessed by MRI

Time Frame: Day 2 (within two weeks after the intervention)

BOLD functional MRI and structural MRI

Study Sites (1)

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