跳至主要内容
临床试验/NCT01938339
NCT01938339Unknown不适用

Development of Clinical Assessment Technique Using Multi-radiotracer PET/MR in Prostate Cancer

Seoul National University Hospital2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2012年5月最近更新:
适应症

试验速览

阶段
不适用
入组人数
60
试验地点
2
主要终点
accuracy of PET/MR predicting localization and staging of prostate cancer

研究概览

简要总结

To development of clinical assessment technique using multi-radiotracer positron emission tomography/magnetic resonance (PET/MR) in prostate cancer

  • to establish the optimal imaging technique of PET/MR using multiple radioactive tracers for prostate cancer
  • to establish the imaging biomarker using PET/MR for clinical assessment of prostate cancer and early detection of recurrent prostate cancer

详细描述

To establish the optimal imaging technique of PET/MR using multiple radioactive tracers for prostate cancer

  • Recruiting 30 patients with prostate cancer ahead to radical prostatectomy
  • PET/MR using 18F-choline with dedicated prostate MRI in all patients
  • PET/MR using 18fluoride(F)-fluorodeoxyglucose(FDG)in all patients after 2-7 days
  • PET/CT using 18F-FDG in all patient immediate after 18F-FDG PET/MR
  • outcome assessment: comparison of scan time, image quality, tumor detection rate, standardized uptake values of lesions
  • establishing optimal imaging technique for prostate PET/MR

To establish the imaging biomarker using PET/MR for clinical assessment of prostate cancer

  • comparison of findings on PET/MR, MRI and PET/CT with pathological mapping after radical prostatectomy
  • outcome assessment: accuracy of PET/MR for localization and staging of prostate cancer compared with MRI only and PET/CT only

To establish the imaging biomarker using PET/MR for early detection of recurrent prostate cancer

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

性别
Male
接受健康志愿者

入选标准

  • patient with prostate cancer before treatment
  • patient with prostate cancer treated
  • patient with prostate cancer recurrent

排除标准

  • patient with contraindication for MRI
  • Patient with severe renal impairment

结局指标

主要结局

accuracy of PET/MR predicting localization and staging of prostate cancer

时间窗: 1 week after radical prostatectomy

analysis of accuracy of PET/MR predicting localization and staging of prostate cancer by comparison of PET/MR findings with pathological mapping images after radical prostatectomy

次要结局

  • accuracy of early detection and localization of recurrent prostate cancer(1 week after PET/MR imaging)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验