Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED)
Phase 3
Completed
- Conditions
- Ocular HypertensionGlaucoma
- Registration Number
- NCT00108017
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Brief Summary
This study is comparing 2 medications for glaucoma and how effective they are at controlling glaucoma over the course of an entire day.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 330
Inclusion Criteria
- Patients with glaucoma or ocular hypertension
Exclusion Criteria
- Other eye conditions
- Poor vision
- Recent eye surgery
- Use of contact lenses
- Nursing or pregnant women
- Use of some other selected medications
- Drug or alcohol abuse
- Asthma
- Slow heart beat
- Allergy or previous reaction to study drugs
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method 24 hour diurnal IOP reduction after 8 weeks of treatment After 8 weeks of treatment
- Secondary Outcome Measures
Name Time Method IOP reduction a) from baseline at 6 weeks; b) comparison with timolol; c) comparison day versus night At 6 weeks