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Validation of the german version of ESC Screener 2.0 in patients with coronary heart disease

Conditions
I25.1
Atherosclerotic heart disease
Registration Number
DRKS00023740
Lead Sponsor
Klinik und Poliklinik für Psychosomatik und Psychotherapie, Universität zu Köln
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
314
Inclusion Criteria

patients who underwent a heart catheterization independent of the indication
- german speaking

Exclusion Criteria

- palliative setting of other reason
- non german speaking

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
-a confirmatory factor analysis will be run incorporating all constructs, examining a bi-factor model (screener – full scale). The hierarchical omega value will then indicate the percentage of variance in both scales explained by the same underlying latent factor [1].<br>-for test-retest- reliability intra-class-correlations will be calculated for the continuous scores on the screener subscales with the matching full-scale instrument. This will enable conclusions about rank order validity<br>-for the depression and anxiety thresholds as well as type D personality ROC curves will be generated to determine the optimal levels of sensitivity and specificity and with those define cut-off values using the Youden´s J statistic. Additionally, predictive values will be calculated<br>
Secondary Outcome Measures
NameTimeMethod
-to estimate the agreement between the screener and the gold standard scales -depending on the structure of missing values-Cohen´s kappa or Krippendorff´s alpha values will be calculated for the constructs with given thresholds.<br>-comparison of patients at risk for CHD vs manifest CHD – exploratory analysis of the above mentioned (ROC-curves, agreement measures)<br>-exploratory sensitivity analyses of different weighting approaches in comparison to Youden´s J statistic<br><br>
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