Examination concerning dosage of dexamethasone when Fosaprepitant and Palonosetron are used together for nausea and vomiting induced chemotherapy for head and neck cancer.
Not Applicable
- Conditions
- head and neck cancer
- Registration Number
- JPRN-UMIN000008080
- Lead Sponsor
- Hiroshima University Hospital Department of Otorhinolaryngology Head and Neck Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
(a) Vomiting prior to chemotherapy within 24hours (b) They have the factor (tumor of the brain, street trouble of the gut, ulcus pepticum of briskness, and cerebral metastasis, etc.) that nausea and vomiting are caused besides the cancer chemotherapy (c) They have an associated symptom (ex infectious disease) patient who cannot administer dexamethasone. (d) judged by the investigator to be inappropriate for this study (e) pimozide is being administered.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete response rate of vomiting within 120hours from cisplatin administration
- Secondary Outcome Measures
Name Time Method (a)Complete response rate of vomiting within 24hours,and 24-120 hours from cisplatin administration. (b)Level of nausea (c)Level of anorexia (d)The proportion of patients receiving rescue medication. (e)Evaluation of nausea and vomiting of each course on 10 point scale. (f)adverse event