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临床试验/NCT00966745
NCT00966745已完成不适用

Effect of Milrinone During Living Donor Hepatectomy Using a Low Central Venous Pressure Technique

Seoul National University Hospital1 个研究点 分布在 1 个国家目标入组 38 人开始时间: 2008年1月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
38
试验地点
1
主要终点
condition of surgical field

研究概览

简要总结

Maintaining a low central venous pressure during living donor hepatectomy is routine practice. The investigators tried to test the hypothesis that using milrinone to maintain a low central venous pressure (CVP) during is associated with a superior surgical field and less blood loss.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Triple (Participant, Care Provider, Investigator)

入排标准

年龄范围
19 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Living liver donors

排除标准

  • Donors with concurrent cardiac, pulmonary, and urologic disease
  • Hepatectomy performed laparoscopically

研究组 & 干预措施

milrinone

Active Comparator

milrinone infusion

干预措施: milrinone (Drug)

placebo

Placebo Comparator

干预措施: placebo (Drug)

结局指标

主要结局

condition of surgical field

时间窗: intraoperative period (from the start of surgery to end of living donor hepatectomy)

次要结局

  • the use of vasopressor and diuretics to maintain hemodynamic stability and low CVP status, respectively(intraoperative period (from the start of surgery to end of living donor hepatectomy))

研究者

申办方类型
Other

研究点 (1)

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