From muscle strength to power: assessment and underlying determining properties to understand muscle age related functional decline
Completed
- Conditions
- spierverouderingmuscle ageingsarcopenia10028302
- Registration Number
- NL-OMON35963
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
healthy young adults, age ranges 20 - 30 yrs
eldery, age ranges 70 - 80 yrs, free living, ADL independent
Exclusion Criteria
MMSE (mini-mental state examination) < 23
SPPB (short-physical performance battery) < 10
sports on highly competitive level
sedentary lifestyle
co-morbidity: neurological disorders, metabolic disorders, arthritis, cancer
medication: immunosuppressive drugs, insulin
fracture last half year
hip/knee replacement last two years
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The difference in maximal muscle power between young and old during both<br /><br>release experiments and continuous movements.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Power will be related to activation dynamics, short-range stiffness, controller<br /><br>function, functional fibre typing (by<br /><br>measuring short-range stiffness and activation dynamics) and handgrip strength.<br /><br>Also test-retest reproducibility will be assessed.</p><br>