Leveraging Behavioral Economics to Equitably Implement Cascade Screening in Individuals With Familial Hypercholesterolemia in Partnership With the Family Heart Foundation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Aim 1 Qualitative Interview Outcome: Perspectives on cascade screening
研究概览
简要总结
Design, refine, and pilot the two implementation approaches using behavioral economics and then seek further feedback prior to the proposed clinical trial, consistent with these recommendations.
Aim 1. Co-design both implementation strategies using behavioral economics in partnership with the Family Heart Foundation and key partners from diverse backgrounds.
Aim 2. Pilot strategies with 20 patients with high cholesterol and/or with familial hypercholesterolemia (FH) to ascertain feasibility, acceptability, appropriateness.
详细描述
Aim 1. Conduct interviews with patients with high cholesterol and/or FH and clinicians to identify common barriers and facilitators for individuals to engage in cascade screening. These activities will occur in the first 7 months and will serve as inputs into the design of the implementation strategies to ensure that strategies address determinants identified in the interviews.
Aim 2. To maximize success, pilot test the implementation strategies and the planned data collection approaches.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with high cholesterol and/or FH (i.e., probands; Aim 1 Interviews, Aim 2 Pilot Testing Strategies, Aim 2 Interviews). Adults aged 18 and older with clinically diagnosed FH and/or high cholesterol who are treated within Penn Medicine.
- •Family Members (Aim 2 Pilot Testing Strategies, Aim 2 Interviews). Adults aged 18 and older who have a family member who has been identified as a patient with high cholesterol and/or FH who is treated within Penn Medicine (i.e., family members of probands).
排除标准
- 未提供
结局指标
主要结局
Aim 1 Qualitative Interview Outcome: Perspectives on cascade screening
时间窗: 1-time interview to last 1 hour
We will learn about the perspectives on cascade screening from clinicians and patients with high cholesterol and/or FH (probands) via qualitative interview.
Aim 2 Mini-Pilot Outcome: Reach
时间窗: 3 months
We define reach as the proportion of probands who have at least one family member who completes cascade screening.
Aim 2 Mini-Pilot Outcome: Engagement
时间窗: 3 months
We define engagement as the number of patients with FH and/or high cholesterol (probands) who respond to at least one outreach attempt.
Aim 2 Mini-Pilot Outcome: Perspectives on implementation strategies
时间窗: 1-time interview to last approximately 15-30 minutes
We will learn about the perspectives on the implementation strategies (health system-mediated, Family Heart Foundation-mediated) - including their perceived acceptability, appropriateness, and feasibility - of patients with high cholesterol and/or FH (probands) and family members via qualitative interview.
次要结局
未报告次要终点
研究者
Rinad Beidas
Ralph Seal Paffenbarger Professor and Chair, Department of Medical Social Sciences
Northwestern University