Comparison the effect of Letrozole with Misoprostol on induction of first trimester abortion in pregnancy
Phase 2
- Conditions
- Therapeutic Abortion.Therapeutic/Medical Abortion (termination of pregnancy)
- Registration Number
- IRCT2015050119037N8
- Lead Sponsor
- Investigator
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
Pregnant women with 18 to 34 years of age with nonviable pregnancy under 12 weeks from the first day of last menstrual period.
Exclusion criteria:
History of systemic diseases or presence of acute conditions that require any urgent intervention and treatment.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The interval between induction and abortion beginning and opening of cervical internal os. Timepoint: Until 24 hours after receiving Misoprostol, every 1 hour. Method of measurement: Physical examination.;The interval between induction and complete abortion. Timepoint: Until 24 hours after receiving Misoprostol, every 1 hour. Method of measurement: Sonography.
- Secondary Outcome Measures
Name Time Method Gastrointestinal problems (nausea or vomiting). Timepoint: From receiving Letrozole until 24 hours after receiving Misoprostol. Method of measurement: Objective.