The influence of hyoscine N-butylbromide on colonoscopic polyp detection ratio
Completed
- Conditions
- Colonic Polypslarge bowel polyps1001793410017987
- Registration Number
- NL-OMON36608
- Lead Sponsor
- Deventer Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 672
Inclusion Criteria
1. Patiënt is routinely referred for colonoscopy by GP or specialist, and the correct indication as well possible contraindications for the procedure have been verified by a gastroenterologist, which is a standard procedure in the Deventer Hospital
2. Patiënt is able to understand and give informed consent
3. The age should be above 30.
Exclusion Criteria
1. Pregnancy
2. Myasthenia Gravis
3. Exacerbation of inflammatory bowel disease
4. (Suspicion of) active diverticulitis
5. Expectation of an estimated probability of complete colonoscopy of less than 50%, e.g. by the presence of a stenosis
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Poly detection ratio: the percentage of colonoscopies with at least one<br /><br>colonic polyp as compared to the total number of colonoscopies.<br /><br>(Ref: colonoscopic Withdrawal Times and Adenoma Detection during Screening<br /><br>Colonoscopy. Barclay RL, Vicari JJ, Doughty AS, Johanson JF, Greenlaw RL. NEJM<br /><br>2006;355 2533-2541)</p><br>
- Secondary Outcome Measures
Name Time Method <p>1 The total number of polyps seen during colonoscopy, divided by the total<br /><br>number of colonoscopies<br /><br>2. The total number of polyps removed during colonoscopy, divided by the total<br /><br>number of colonoscopies<br /><br>3. The total number of polyps retrieved for pathological investigation, diverd<br /><br>by the total number of colonoscopie<br /><br><br /><br>These parameters wille be expressed in a percentage and will be determined for<br /><br>polyps with a stalk and for flat polyps, acoording to their resepctive sizes (<br /><br>(< 5 mm, 5-10 mm, > 10 mm).<br /><br>(Ref: Colonoscopic Withdrawal Times and Adenoma Detection during Screening<br /><br>Colonoscopy. Barclay RL, Vicari JJ, Doughty AS, Johanson JF, Greenlaw RL. NEJM<br /><br>2006; 355:: 2533-2541)</p><br>