Prevalence of Fuchs Endothelial Corneal Dystrophy in a Population of Dermatology Patients.

Completed

• Conditions: Fuchs Endothelial Corneal Dystrophy

• Registration Number: NCT07117071
• Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Brief Summary

The prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) varies from 3.7 to 21.6% of adults depending on the population studied (country and age class), the method of diagnosis and the definition adopted. In the absence of available data for France, we analyzed the prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) in a specific sub-population.

Detailed Description

The Primary purpose is to Estimate the prevalence of Fuchs' endothelial dystrophy in the French population in dermatology population.

Study Timeline

• Study Start: 2024-01-02
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31
• Status Verified: 2025-08
• Study First Submitted: 2025-08-05
• Study First Submitted QC: 2025-08-05
• Last Update Submitted: 2025-08-05
• Study First Posted: 2025-08-12
• Last Update Posted: 2025-08-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1200

Inclusion Criteria

• Patient with screening of Fuchs endothelial corneal dystrophy

Exclusion Criteria

• Patients under guardianship
• Patients unable to receive informed consent
• Patients with anterior segment pathology (declarative) (the eye concerned will not be photographed)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dark spot in specular microscopy	Years: 1	Dark sport or guttae after specular microscopy in parallel with the dermatological consultation

Secondary Outcome Measures

Name	Time	Method
Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of age	Years: 1	Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of age. Data of medical record will be analyzed.
Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of gender	Years: 1	Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of gender.; Data of medical record will be analyzed.
Correlation between Fuchs endothelial corneal dystrophy (FECD) and skin pathology	Years: 1	Correlation between Fuchs endothelial corneal dystrophy (FECD) and skin pathology.; Data of medical record will be analyzed.

Trial Locations

Locations (1)

CHU Saint-Etienne; 🇫🇷 Saint-Étienne, France