NCT05236283已完成不适用
Duration of Antimicrobial Treatment for Bloodstream Infections in Swiss Critically Ill Patients - Retrospective Double Center Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 395
- 试验地点
- 1
- 主要终点
- Antibiotic Treatment Duration
研究概览
简要总结
The objectives of the retrospective cohort study is to describe the actual current practice of antibiotic treatment duration for bloodstream infections in critically ill patients at two tertiary hospitals (ICU Inselspital Bern and ICU CHUV Lausanne), to examine patient, pathogen and infectious syndrome factors associated with selection of shortened treatment duration, and to describe the expected time course of clinical resolution among bacteremic patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient has a positive blood culture with a pathogenic organism Patient is critically ill at the time the blood culture was collected as defined by the following:
- •was treated at the ICU/IMC at the time of blood culture collection;
- •or has been admitted to ICU/IMC in the 48 hours after blood culture collection
排除标准
- •Patient has a single positive blood culture with a common contaminant organism:
- •coagulase negative staphylococci;
- •Bacillus spp.;
- •Corynebacterium spp.;
- •Propionibacterium spp.;
- •Aerococcus spp.;
- •Micrococcus spp.
- •Explicit documentation that the patient does not want to participate in any study
结局指标
主要结局
Antibiotic Treatment Duration
时间窗: Hospital discharge, expected to be on average ca. 15-20 days
Days of adequate antibiotic treatment in Patients with Bacteremia
次要结局
- Days of hospital stay(Hospital discharge, expected to be on average ca. 15-25 days)
- Days of ICU stay(ICU discharge, expected to be on average ca. 5-15 days)
研究者
研究点 (1)
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