Cyanoacrylate and Laser and Dentin Sensitivity

Not Applicable

Completed

• Conditions: Dentin Hypersensitivity; Dentin Sensitivity
• Interventions: Radiation: Laser; Other: Cyanoacrylate

• Registration Number: NCT01111474
• Lead Sponsor: Federal University of São Paulo

Brief Summary

This study aimed to evaluate the effectiveness of two treatments for dental hypersensitivity: cyanoacrylate (Super Bonder®) compared with use of low intensity laser treatment (LILT). As the cyanoacrylate is a lower cost treatment, the hypothesis in investigation is if this product is equally effective as the laser treatment.

Detailed Description

The present study included 62 patients (15 male and 47 females, aged 12 to 60 years). The initial cervical dentin hypersensitivity was checked throughout a thermal test (air blast). The 434 teeth included were that with a score ≥5 in a numerical scale rating of pain. Teeth were randomly assigned according quadrants (split mouth design) - 216 were allocated to LILT group and 218 for the Super Bonder® group. Thermal tests with a tetrafluoroethane spray (Endo-Ice®) and air blast were performed and considered as baseline. Pain parameters were recorded using a numerical scale rating with 24 hours, 30, 90 and 180 days after the interventions. Quality of life of the patients was also assessed with the use of OHIP-14 at baseline and after 180 days.

Study Timeline

• Study Start: 2008-08
• Primary Completion: 2008-12
• Study Completion: 2009-02
• Study First Submitted: 2010-04-20
• Study First Submitted QC: 2010-04-26
• Study First Posted: 2010-04-27
• Results First Submitted: 2012-02-13
• Status Verified: 2020-08
• Results First Submitted QC: 2020-08-13
• Last Update Submitted: 2020-08-13
• Results First Posted: 2020-08-17
• Last Update Posted: 2020-08-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

1. patients should be in good general and dental health;
2. present complaints of dental sensitivity to cold, sweet, acidic foods and brushing;
3. present complaints of pain in teeth located in different quadrants;
4. manifest pain or discomfort upon application of the triple syringe air jet;
5. not be in current use of desensitizing agents.

Exclusion Criteria

1. presence of extensive restorations and carious lesions in the sensitive teeth;
2. undergoing orthodontic treatment;
3. frequent use of analgesics, antidepressants and anti-inflammatory drugs;
4. presence of gingival inflammation;
5. non-consent of patient.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Laser	Laser	3 Low intensity laser application (48 hour interval). The application of 1Joule/cm\^2 was performed for eight seconds at three points along the dental neck, using the infrared wavelength (795nm)
Cyanoacrylate	Cyanoacrylate	3 applications of cyanoacrylate (48 hours interval)at the cervical region of the sensitive tooth

Primary Outcome Measures

Name	Time	Method
Change of the Pain Sensitivity	Baseline and 180 days	Change in pain experienced by the participants was calculated as the difference between baseline level of pain sensitivity and after 180 days. Pain was recorded using a numerical pain assessment scale with range between 0 (no pain) to 10 (worst possible pain). The higher the numbering the worse the result.

Secondary Outcome Measures

Name	Time	Method
Quality of Life Improvement	Baseline and 180 days	Difference between the level of quality of life - Oral Health Impact Profile "OHIP" at baseline and 180 days. OHIP-14 total scale ranges from 0 to 56 points with higher scores indicating a poorer oral health-related quality of life. The response format uses a Likert-type frequency scale such as follows: very often = 4, fairly often = 3, occasionally = 2, hardly ever = 1, never = 0. Total score is obtained by summing the response codes of the 14 items constituting the measure.