Flupirtine vs Tramadol in Knee Osteoarthritis : A Randomized Controlled Trial

There was no sponsor in this trial0 个研究点目标入组 90 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1.Clinically diagnosed cases of primary early symptomatic OA affecting at least one knee joint (in case of bilateral knee involvement, the more symptomatic knee was scored as the â??signal kneeâ??).
•2.Sex: Either sex was included
•3. Knee joint pain present for at least one month in the preceding three months with at least one of the following: morning stiffness less than 30 min or knee crepitus
•4.Knee pain on movement of intensity at least 35 mm on a 100 mm in VAS scale

•1. Secondary OA, such as due to injury, inflammatory condition, metabolic or rheumatic disease, osteonecrosis, Pagetâ??s disease, hemophilia etc.
•2. Non-OA causes of knee pain in the signal knee (e.g. bursitis, fibromyalgia, osteonecrosis, etc)
•3. Prior intra-articular injection of hyaluronic acid / steroid / joint lavage in the study knee any time in the past three months.
•4. Knee injury or diagnostic arthroscopy of signal knee within 6 months preceding enrollment or knee surgery (including arthroscopic surgery requiring an incision of the internal joint components) in the study knee, at anytime.
•5.Severe and advanced OA disease, defined as joint space width < 2 mm or deformed joint, or disease necessitating knee surgery in the current year.
•5. Serious concomitant disease of vital organs.
•6. Subject unlikely to provide informed consent, follow the study protocol or any other criteria, which in the opinion of the investigator, was not conducive to enrollment of a particular subject into the trial.

发起方

There was no sponsor in this trial