NCT03826797招募中不适用
Correlation Between Trans Esophageal Pressure and Non-invasive Respiratory Support Failure in Patients With Acute Hypoxic Respiratory Failure
University of Modena and Reggio Emilia1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2016年10月16日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Esophageal pressure impact on non invasive respiratory support (NRS) failure
研究概览
简要总结
This study aims at assessing the correlation between trans esophageal pressure and related respiratory mechanics (including, among others, nasal pressure-Pnose) and non-invasive respiratory support failure in patients with acute hypoxic respiratory failure of different etiology (including COVID-19).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years
- •Acute hypoxic respiratory failure (P/F < 200)
排除标准
- •Acute pulmonary edema
- •Chest wall deformities
- •Immediate need for Mechanical Ventilation
- •Pregnancy
- •Hypercapnic RF
结局指标
主要结局
Esophageal pressure impact on non invasive respiratory support (NRS) failure
时间窗: 24 hours
Correlation between esophageal pressure values within 24 hours from NRS start and NRS failure
次要结局
- Dynamic compliance impact on NRS failure(24 hours)
- Transpulmonary pressure impact on NRS failure(24 hours)
- Dynamic mechanical power impact on NRS failure(24 hours)
- Pnose impact on NRS failure(24 hours)
- Correlation between nasal pressure (Pnose) and esophageal pressure(24 hours)
研究者
Alessandro Marchioni
Principal Investigator
University of Modena and Reggio Emilia
研究点 (1)
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