NCT01726205已完成4 期
Perioperative Pregabalin and Continuous Wound Infusion for Pain Control Following Thoracotomy
Attikon Hospital1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2008年10月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Pain control
研究概览
简要总结
The purpose of this study is to assess the efficacy of pregabalin or pregabalin and continuous wound infusion versus placebo for analgesia following thoracotomy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients scheduled for a thoracotomy,
排除标准
- •age >70 years
- •BMI > 30
- •preoperative Hb < 10 mg/dL
- •preexistent chronic pain
- •neurologic disease
- •chronic assumption of alcohol
- •treatment with analgesics, anxiolytics, sedatives, antidepressants, or calcium channel inhibitors
研究组 & 干预措施
pregabalin
Active Comparator
perioperative pregabalin starting the evening before surgery, and for five days postoperatively
干预措施: Pregabalin and normal saline infusion, PRG (Drug)
pregabalin and continuous wound infusion
Active Comparator
Pregabalin as previous group and continuous infusion of ropivacaine 0.2% via a wound catheter
干预措施: Pregabalin and ropivacaine 02% infusion (Drug)
placebo
Placebo Comparator
Placebo drug and normal saline infusion
干预措施: Placebo drug, normal saline infusion (Drug)
结局指标
主要结局
Pain control
时间窗: 5 days postoperatively
次要结局
- morphine consumption(3 days postoperatively)
研究者
Sidiropoulou Tatiana
Lecturer in Anesthesiology, University of Athens
Attikon Hospital
研究点 (1)
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