Flavour processing in healthy males, investigated with fMRI.

Completed

Conditions: Er wordt geen aandoening bestudeerd.
n.v.t.

Registration Number: NL-OMON41200

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 20

Inclusion Criteria

Caucasian, right handed, normal (or corrected to normal) vision, healthy, BMI 18-25 kg/m2, normal sense of taste and smell, non-smoking, fMRI compatible, no history of neurological or psychiatric disorders, Male, Age range: 18-30, fluent in dutch.

Exclusion Criteria

MR incompatable (posibility of any incompatible metal objects inside the body),
History of psychiatric disorders,
History of taste-related disorders,
Allergies against ingredients of the stimuli,
Smokers.
Wearing glasses (lenses are allowed)
Alcohol/drug abuse

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are: the flavors administered to the subjects (two<br /><br>flavors, one pleasant one unpleasant, plus one neutral), flavor intensities<br /><br>(five concentrations, plus one neutral), the perceived pleasantness and<br /><br>intensity of each flavor solution, the brain activity corresponding to each<br /><br>flavor intensity and pleasantness during administration. In addition the brain<br /><br>activity corresponding to exposure to each IAPS image as well as the ratings of<br /><br>reward and disgust at exposure to these images is used.<br /><br><br /><br>The outcome of the study (endpoints) will consist of:<br /><br>- The neural activity patterns associated with flavor intensity and valence;<br /><br>- A comparison of the reward and disgust networks found in response to flavors<br /><br>and images.</p><br>

Secondary Outcome Measures