Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode

Completed

• Conditions: Safety Issues

• Registration Number: NCT03465475
• Lead Sponsor: Inonu University

Brief Summary

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

Detailed Description

After the ethical approvel 60 adult patients scheduled for hepatectomy will be taken to study. Patients will be monitored after they are taken to the operating room (ECG, NIBP, SpO2, Body Temp, BIS, NIRS, PVI, PI, ORI). After the anesthesia induction and tarakeal entubation, first twenty patient will take 300 mL fresh gas flow with AGC mode (group 1), Second twenty patient will take 600 mL fresh gas flow with AGC mode (group 2), third twenty patient will take 600 mL fresh gas flow with manually. Hemodynamic and gas consumption data will be recorded. An operating room will be reserved for this study.

Study Timeline

• Study First Submitted: 2018-02-01
• Study First Submitted QC: 2018-03-13
• Study First Posted: 2018-03-14
• Study Start: 2018-07-01
• Primary Completion: 2020-10-30
• Study Completion: 2021-03-01
• Status Verified: 2021-08
• Last Update Submitted: 2021-08-24
• Last Update Posted: 2021-08-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Adult patients undergoing hepatectomy with general anesthesia

Exclusion Criteria

• Essential data missing
• Patient participating in other research projects
• Drug allergy
• Anesthetic complication story

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amount of used anesthetic gas (desflurane)	Through study completion, an average of 2 month	Amount of used desflurane will be determined in milliliter by anesthesia machine (Maquet Flow i40) for each patient.

Secondary Outcome Measures

Name	Time	Method
Heart rate	Through study completion, an average of 2 month	Heart rate/min
Mean arterial pressure	Through study completion, an average of 2 month	Mean arterial pressure (mm/Hg)
Peripheral oxygen saturation	Through study completion, an average of 2 month	Peripheral oxygen saturation (%)

Trial Locations

Locations (1)

Inonu Univercity; 🇹🇷 Malatya, Turkey