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Measuring the survival of transfused red blood cells in patients with Sickle cell disease and b-Thalassemia: A Biotin Label approach

Completed
Conditions
beta-thalassemia
Sickle cell disease
10018902
Registration Number
NL-OMON50011
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
15
Inclusion Criteria

Patients with sickle cell disease or beta-thalassemia on chronic transfusion
scheme, >18 jaar

Exclusion Criteria

No informed consent
No venous access

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>- Assessment of survival of transfused RBCs in patients with sickle cell<br /><br>disease and *-thalassemia</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>- Determination of effect of antigen matching on survival of transfused units<br /><br>- Inflammatory response on transfused RBCs </p><br>
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