Drug delivery through root canal treated tooth
- Conditions
- Health Condition 1: K044- Acute apical periodontitis of pulpal origin
- Registration Number
- CTRI/2023/03/050279
- Lead Sponsor
- SAJANI RAMACHANDRA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients reporting with pulpitis
2. Consenting adult patients above the age of 18 years
3. Patients requiring root canal treatment for maxillary 1st molar
4. Patients with dental caries with pulp exposure
5. Patients with no contra-indications for root canal procedure
6. Patients who have no known systemic problems and are not on regular medications
1. Patients with periapical lesions not involving the pulp
2. Patients with known allergy to metronidazole
3. Patients who have taken metronidazole or any other drugs for the past 72 hours
4. Patients who have bleeding disorders, liver and kidney problems or are on anti-platelet drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the blood level of orally administered metronidazole with locally administered metronidazole through a drug delivery system at specified time intervals,Timepoint: 30 minutes and 90 minutes
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI