Overal Survival After TAVI According to Sarcopenia

Completed

• Conditions: Sarcopenia; Aortic Valve Stenosis

• Registration Number: NCT05672160
• Lead Sponsor: Nemocnice AGEL Trinec-Podlesi a.s.

Brief Summary

The goal of this observational study is to compare the overal survival after transcatheter aortic valve implantation (TAVI) according to sarcopenia status evaluated from preprocedural CT scans.

The main question it aims to answer is:

• Is CT evaluated sarcopenia an independent predictor of overal survival after TAVI?

Detailed Description

The patients suffering from aortic valve stenosis, that are not eligible for cardiosurgery were indicated to miniinvasive transcatheter aortic valve implantation (TAVI). The follow up of 930 patients were done in time interval from 1 to 11 years. In every patient the preprocedural CT scans were done. From these CT scans the L3 cross sections will be used for sarcopenia evaluation. Then we will statisticaly evaluate the overal survival after TAVI procedure in the relation with sarcopenia status. We will answer the main question: Is CT evaluated sarcopenia an independent predictor of overal survival after TAVI?

Study Timeline

• Study Start: 2022-01-01
• Status Verified: 2023-01
• Primary Completion: 2023-01-01
• Study Completion: 2023-01-02
• Study First Submitted: 2023-01-03
• Study First Submitted QC: 2023-01-03
• Last Update Submitted: 2023-01-03
• Study First Posted: 2023-01-05
• Last Update Posted: 2023-01-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 930

Inclusion Criteria

• patients udergone TAVI procedure

Exclusion Criteria

• patients with incomplete TAVI procedure, patients without clinical follow up

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overal survival	11 years	Time from the TAVI procedure to death

Trial Locations

Locations (1)

AGELTrinecPodlesi; 🇨🇿 Třinec, Česká Republika, Czechia