Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation

• Conditions: Acute Renal Failure

• Registration Number: NCT04682236
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

Liver transplantation is associated with a modification of the perfusion pressures of the abdominal organs (preoperative portal hypertension in connection with liver pathology, and normalization of the perfusion pressures during surgery). This abrupt change in the infusion regime is probably responsible for an alteration in renal function in some patients, and the identification of renal vascular profiles using Doppler could point to pathological profiles, which should be diagnosed early.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-25
• Status Verified: 2020-12
• Study First Submitted: 2020-12-18
• Study First Submitted QC: 2020-12-18
• Study First Posted: 2020-12-23
• Last Update Submitted: 2020-12-23
• Last Update Posted: 2020-12-28
• Primary Completion: 2022-05-25
• Study Completion: 2022-05-25

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patient of full age (≥18 years)
• Patient operated on at the HUS for a liver transplant, between July 1, 2019 and June 30, 2020.
• Patients having undergone an evaluation of hepatic and renal vascular profiles perioperatively.
• Patients hospitalized in the surgical intensive care unit after hepatic transplant surgery.
• Patient not having expressed, after information, the reuse of his data for the purposes of this research

Exclusion Criteria

• Patient who expressed his opposition to participating in the study
• Patient with suspected obstructive acute renal failure
• Stenosis of renal arteries known at the time
• End-stage renal disease on dialysis
• Impossibility of giving the subject informed information (difficulties in understanding the subject, etc.)
• Subject under safeguard of justice

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Retrospective analysis of the development profiles of renal dopplers in perioperative liver transplantation	Files analysed retrospectily from July 1st, 2019 to June 30, 2020 will be examined

Trial Locations

Locations (1)

Strasbourg University Hospitals - Anesthesia-intensive care unit; 🇫🇷 Strasbourg, France