Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts in Respiratory Allergy Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Mahidol University
- Enrollment
- 230
- Locations
- 1
- Primary Endpoint
- Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients
Study Overview
Brief Summary
In respiratory allergy patients, skin prick test results of local rat and mouse allergen extracts are not significant different from imported ones
Detailed Description
Many researches proposed that rodent deteriorate symptoms in patients with respiratory allergy who sensitized. The test that can identify rodent sensitization will be very useful. The investigators found lots of problems from imported mouse and rat allergen extract, eg. expensive cost and hard to find importing agency in Thailand. Making own local allergen extract will be the good solution for the country. This study aim to compare the results of locally rat and mouse allergen to imported ones.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Diagnostic
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 3 Years to 60 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients age 3 to 60 years old who diagnosed with asthma or allergic rhinitis
- •Patient must not take these following medication at least 7 days before doing the skin prick test: antihistamine, oral corticosteroid (more than 20 mg/day of prednisolone), topical steroid that was apply on skin test area.
Exclusion Criteria
- •Pateints who have other chronic underlying disease e.g. obesity, heart disease and liver disease
- •Patient with allergic asthma who is still uncontrollable.
- •Patient with active severe atopic dermatitis
- •Patient who are pregnant or in lactating period
- •Patient or parent deny to join in the study
Arms & Interventions
Imported rat and mouse skin test
All patients receive imported skin prick test for mouse and rat. The result were recorded and compared to the local one.
Intervention: rat and mouse skin test (Diagnostic Test)
Local rat and mouse skin test
All patients receive local skin prick test for mouse and rat. The result were recorded and compared to the imported one.
Intervention: rat and mouse skin test (Diagnostic Test)
Outcomes
Primary Outcomes
Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients
Time Frame: 1 year
Compare the results of locally rat and mouse allergen to imported ones.
Secondary Outcomes
No secondary outcomes reported
Investigators
Nualanong Visitsunthorn
Professor
Mahidol University