Comparison of Skin Prick Testing and Intradermal Skin Test Result of Local and Imported Insect Allergen Extracts in Patients With Severe Insect Sting Allergy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Mahidol University
- Enrollment
- 27
- Locations
- 1
- Primary Endpoint
- Comparison of positive skin test results of local and commercial insect allergen extracts
Study Overview
Brief Summary
Comparison the results of skin prick testing and Intradermal skin test result of local and imported insect allergen extracts in patients with serious insect sting allergy reactions
Detailed Description
The patients with serious insect sting allergy reactions were evaluated and skin prick test and intradermal test with local and imported insect allergen extracts were performed. Specific IgE for insects was also performed. The results of skin prick testing and Intradermal skin test of local and imported insect allergen extracts were compared. The results also compared with specific IgE to insects
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Diagnostic
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Masking Description
None of the patients and participants know the type of insect allergen extracts used in skin prick and intradermal test
Eligibility Criteria
- Ages
- 5 Years to — (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with severe insect allergy reaction
- •Allow being done skin test and blood foe specific IgE
Exclusion Criteria
- •Serious systemic diseases
- •severe asthma
- •pregnant or nursing
- •severe and extended skin lesion
Arms & Interventions
Skin test with local extract
Skin prick test and intradermal test with local stinging insect allergen extracts that develop in Immunological division of Siriraj hospital, mahidol University
Intervention: Local insect allergen extracts skin test (Diagnostic Test)
Skin test with commercial extract
Skin prick test and intradermal test with commercial stinging insect allergen extracts that order from ALK company
Intervention: Local insect allergen extracts skin test (Diagnostic Test)
Outcomes
Primary Outcomes
Comparison of positive skin test results of local and commercial insect allergen extracts
Time Frame: 1 year
Measure wheal size of skin test of local and commercial insect allergen extracts then compare the positive result and wheal size between local and commercial extracts.
Secondary Outcomes
No secondary outcomes reported
Investigators
Nualanong Visitsunthorn
Professor
Mahidol University