Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts and Specific IgE
- Conditions
- Immediate Type Hypersensitivity
- Registration Number
- NCT02764827
- Lead Sponsor
- Mahidol University
- Brief Summary
Pollen allergen extracts are prepared locally and checked for efficacy by comparison to imported allergens and specific IgE.
- Detailed Description
Skin prick test (SPT) and specific IgE (sIgE) are approved for evaluation of allergen sensitization. Local allergen extracts are cheaper and more available but need standardization. Pollen allergen extracts: Bermuda, Johnson and careless weed are locally prepared and compared mean wheal diameter of skin prick test to imported allergens and also to specific IgE.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 68
- Positive skin prick test to Bermuda or Johnson or careless weed
- Chronic diseases such as heart disease, liver, renal and severe sepsis
- Severe allergic symptoms such as anaphylaxis
- Extensive skin rashes
- Pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean wheal diameter of local and imported grass and weed pollens 18 months compare mean wheal diameter of skin prick test of different concentration among local, imported allergen extract and specific IgE levels of Bermuda grass, Johnson grass and careless weed
sIgE levels of Bermuda grass,Johnson grass and careless weed 18 months Measure level of sIgE of Bermuda grass,Johnson grass and careless weed and compare to SPT results
- Secondary Outcome Measures
Name Time Method