Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts (Bermuda ,Johnson Grasses and Careless Weed) With Specific IgE Levels.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 68
- 主要终点
- Mean wheal diameter of local and imported grass and weed pollens
研究概览
简要总结
Pollen allergen extracts are prepared locally and checked for efficacy by comparison to imported allergens and specific IgE.
详细描述
Skin prick test (SPT) and specific IgE (sIgE) are approved for evaluation of allergen sensitization. Local allergen extracts are cheaper and more available but need standardization. Pollen allergen extracts: Bermuda, Johnson and careless weed are locally prepared and compared mean wheal diameter of skin prick test to imported allergens and also to specific IgE.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Positive skin prick test to Bermuda or Johnson or careless weed
排除标准
- •Chronic diseases such as heart disease, liver, renal and severe sepsis
- •Severe allergic symptoms such as anaphylaxis
- •Extensive skin rashes
- •Pregnancy
结局指标
主要结局
Mean wheal diameter of local and imported grass and weed pollens
时间窗: 18 months
compare mean wheal diameter of skin prick test of different concentration among local, imported allergen extract and specific IgE levels of Bermuda grass, Johnson grass and careless weed
sIgE levels of Bermuda grass,Johnson grass and careless weed
时间窗: 18 months
Measure level of sIgE of Bermuda grass,Johnson grass and careless weed and compare to SPT results
次要结局
未报告次要终点
研究者
Nualanong Visitsunthorn
Professor
Mahidol University