Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts

Not Applicable

Completed

• Conditions: Allergic Rhinitis Due to Animal Hair and Dander
• Interventions: Diagnostic Test: rat and mouse skin test

• Registration Number: NCT03645161
• Lead Sponsor: Mahidol University

Brief Summary

In respiratory allergy patients, skin prick test results of local rat and mouse allergen extracts are not significant different from imported ones

Detailed Description

Many researches proposed that rodent deteriorate symptoms in patients with respiratory allergy who sensitized. The test that can identify rodent sensitization will be very useful. The investigators found lots of problems from imported mouse and rat allergen extract, eg. expensive cost and hard to find importing agency in Thailand. Making own local allergen extract will be the good solution for the country. This study aim to compare the results of locally rat and mouse allergen to imported ones.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2018-05-30
• Study First Submitted: 2018-08-22
• Study First Submitted QC: 2018-08-22
• Study First Posted: 2018-08-24
• Primary Completion: 2019-05-30
• Study Completion: 2019-07-30
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-12
• Last Update Posted: 2019-08-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 230

Inclusion Criteria

• Patients age 3 to 60 years old who diagnosed with asthma or allergic rhinitis
• Patient must not take these following medication at least 7 days before doing the skin prick test: antihistamine, oral corticosteroid (more than 20 mg/day of prednisolone), topical steroid that was apply on skin test area.

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Exclusion Criteria

• Pateints who have other chronic underlying disease e.g. obesity, heart disease and liver disease
• Patient with allergic asthma who is still uncontrollable.
• Patient with active severe atopic dermatitis
• Patient who are pregnant or in lactating period
• Patient or parent deny to join in the study

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Local rat and mouse skin test	rat and mouse skin test	All patients receive local skin prick test for mouse and rat. The result were recorded and compared to the imported one.
Imported rat and mouse skin test	rat and mouse skin test	All patients receive imported skin prick test for mouse and rat. The result were recorded and compared to the local one.

Primary Outcome Measures

Name	Time	Method
Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients	1 year	Compare the results of locally rat and mouse allergen to imported ones.

Trial Locations

Locations (1)

Siriraj Hospital. Mahidol University; 🇹🇭 Bangkok, Thailand