Efficacy of Lyophilized Food Extracts for Skin Prick Tests and Atopy Patch Test at Different Storage Time

Not Applicable

Completed

• Conditions: Food Allergy
• Interventions: Diagnostic Test: skin test with food at different storage times

• Registration Number: NCT03645629
• Lead Sponsor: Mahidol University

Brief Summary

Comparison the result of skin prick tests and atopy patch test of lyophilized food extracts at different storage time (0, 3 and 6 months) after preparation

Detailed Description

Skin prick test were performed with lyophilized food extracts (cow milk, egg white, egg yolk, wheat, soy and shrimp) at different storage time (0, 3 and 6 months) after preparation.

Atopy patch test were performed with lyophilized food extracts (cow milk, egg white, egg yolk, wheat, soy and shrimp) at different storage time (0, 3 and 6 months) after preparation

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Study Start: 2018-01-01
• Study First Submitted: 2018-08-17
• Study First Submitted QC: 2018-08-22
• Study First Posted: 2018-08-24
• Primary Completion: 2019-06-30
• Study Completion: 2019-07-31
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-12
• Last Update Posted: 2019-08-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• mild to moderately severe food allergy patients
• At least positive skin test to one kind of common food (commercial extract)
• Stop antihistamine or corticosteroid (if more than 20mg/day) for at least 7 days

Read More

Exclusion Criteria

• Dermographism
• Severe systemic disease such as autoimmune disease, immune deficiency, malignancy
• Severe dermatitis or large area involment
• pregnancy

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Food skin tests at 3 month	skin test with food at different storage times	the skin test results of food extract at time 3 months after preparation
Food skin tests at 6 month	skin test with food at different storage times	the skin test results of food extract at time 6 months after preparation
Food skin tests at 0 month	skin test with food at different storage times	the skin test results of food extract at time 0 months after preparation

Primary Outcome Measures

Name	Time	Method
skin test result of lyophilized foods at 6 months after preparation	6 month	Perform skin prick test and atopy patch test the patients with lyophilized foods at 0, 3 and 6 months after preparation and compare the results at 6 months to 0 and 3 months.

Trial Locations

Locations (1)

Siriraj Hospital. Mahidol University; 🇹🇭 Bangkok, Thailand