Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1
- Conditions
- Cocaine-Related DisordersDrug Administration ScheduleInfusions, Intravenous
- Registration Number
- NCT00032916
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Brief Summary
The purpose of this study is to conduct a drug interaction study with NS2359 and cocaine in cocaine experienced volunteers.
- Detailed Description
This is a single-center, double-blind, placebo-controlled, randomized, single dose, fixed order, dose escalating inpatient design that will study oral NS2359 in cocaine experienced volunteers.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 24
Male or Female, 18-45 yrs of age; females of child-bearing potential using appropriate method of birth control; be able to understand the procedure and agrees to participate via informed consent; must be cocaine dependent according to DSM-4 criteria; must be capable of providing written consent; must be able to comply with protocol requirement, CPU rules and regulations; must not be currently seeking treatment for cocaine abuse.
Incapable of understanding the informed consent process; Additional criteria available during screening at the site.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pharmacokinetic parameter comparison plasma concentration
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Uniformed Services University of Health Science
🇺🇸Bethesda, Maryland, United States