Biomarkers in Samples From Young Patients With Soft Tissue Sarcoma
Completed
- Conditions
- Sarcoma
- Registration Number
- NCT01342783
- Lead Sponsor
- Children's Oncology Group
- Brief Summary
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
PURPOSE: This research trial is studying biomarkers in samples from young patients with soft tissue sarcoma.
- Detailed Description
OBJECTIVES:
* To identify the key components of driver pathways of primary and secondary soft tissue sarcomas.
* To perform the next-generation sequencing on primary versus normal on undifferentiated sarcomas.
OUTLINE: Genomic DNA and RNA samples from undifferentiated sarcoma tumors are analyzed by next-generation sequencing for somatic mutations. Normal matched lymphocytes and tissue are also analyzed.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence of somatic mutations in driver genes and mutations in other genes that occur individually
- Secondary Outcome Measures
Name Time Method