EFFICIENCY OF DRUGS LIKE FENTANYL AND CLONIDINE WHEN ADDED AS ADJUVANTS TO PREVENT REBOUND PAIN IN PATIENTS UNDERGOING ANORECTAL SURGERIES UNDER SADDLE BLOCK.

Not Applicable

Not yet recruiting

• Conditions: Health Condition 1: K928- Other specified diseases of the digestive system

• Registration Number: CTRI/2023/03/051043
• Lead Sponsor: JSSAHER

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 3 April 2023

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients posted for anorectal surgeries.

-Ability to understand protocol and able to provide voluntary written consent.

-ASA category I and II.

-BMI < 30kg/m2.

-Height 150-170cms.

Exclusion Criteria

-Uncontrolled psychiatric disorders.

-Uncontrolled medical illnesses like uncontrolled diabetes mellitus, uncontrolled hypertension, ischemic heart disease and chronic kidney disease.

-Any contraindication to clonidine i.e. bradycardia.

-Any contraindication to spinal anesthesia like patient refusal, infection at lumbar puncture site, coagulopathies or patients who are on anticoagulants.

-Allergic to local anaesthetics.

-Pregnant and lactating mothers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of clonidine and fentanyl as adjuvants to hyperbaric 0.5% bupivacaine on prevention of rebound pain in anorectal surgeries under saddle block.Timepoint: Starting from spinal anaesthesia till 48hours after completion of surgery.

Secondary Outcome Measures

Name	Time	Method
-To evaluate the post operative pain scores (NRS) for the first 48 hours after surgery after the administration of intrathecal adjuvants such as clonidine and fentanyl in patients undergoing anorectal surgery under saddle block . <br/ ><br>-To assess the time taken for first rescue analgesic. <br/ ><br>-To assess the total dose of rescue analgesic requirement for 48 hours post surgery. <br/ ><br>-To assess the incidence of side effects between the groups receiving hyperbaric bupivacaine alone and in combination with fentanyl and clonidine.Timepoint: Starting from spinal anaesthesia till 48hours after completion of surgery.