A comparative study of effectiveness of Alpha2 agonist (Dexmedetomidine) versus opioid (fentanyl) for awake intubation using flexible bronchoscope

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/03/041196
• Lead Sponsor: Vinayaka missions kirupanda variyar medical college and hospital

Brief Summary

The study was aimed at comparing the effectiveness and safety of Dexmedetomidine versus Fentanyl for awake fiberoptic intubation. Asample size of 60 patients who fulfill the inclusion criteria was included in the study after getting the informed consent. Patients will be randomly allocated into Group A(Dexmedetomidine), Group B(Fentanyl ) 30 each.Ramsay sedation score ,Cough score, Post intubation score , Vital parameters like Heart rate ,Blood pressure , Oxygen saturation will be assessed preoperatively , After drug infusion , post intubation

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-13
• Last Update Posted: 2022-11-03

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

ASA-PS grading 1,2 Mallampati grading 1,2.

Exclusion Criteria

Patient unwilling for the procedure Age<18 and >50 years History of bleeding disorder History of unstable angina Resting heart rate <50/min MP 3,4.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of Dexmedetomidine(1ug/kg)and Fentanyl (1ug/kg) for sedation and patients comfort and compliance during awake fiberoptic intubation	Ramsay Sedation score, Cough Score, Post Intubation Score, BP, Heart Rate, Spo2 for 15 minutes intraoperatively

Secondary Outcome Measures

Name	Time	Method
To monitor complications like respiratory depression, fall in SPO2, bradycardia, hypotension	baseline, after giving study drugs, post intubation

Trial Locations

Locations (1)

Department of Anaesthesiology; 🇮🇳 Salem, TAMIL NADU, India

Department of Anaesthesiology

🇮🇳Salem, TAMIL NADU, India

Sagana S

Principal investigator

9047010702

dr.saganamahesh@gmail.com