A Longitudinal Study in 1st Degree Relatives of Parkinson's Disease (PD) Patients

• Conditions: Parkinson's Disease
• Interventions: Other: neurological examination

• Registration Number: NCT01502384
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

This is a longitudinal study in healthy 1st degree relatives of patients with Parkinson's Disease (PD) carriers of a genetic mutation in genes that are known to increase the risk for PD. The purpose of this study is to explore the association between genetic mutations in the known genes and early preclinical symptoms such as motor, sensory, autonomic, behavioral and cognitive functions.

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-12
• Study First Submitted: 2011-12-28
• Study First Submitted QC: 2011-12-29
• Last Update Submitted: 2011-12-29
• Study First Posted: 2011-12-30
• Last Update Posted: 2011-12-30
• Study Start: 2012-01
• Primary Completion: 2015-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• healthy 1ST degree relatives of PD patients with known genotype that participated in an earlier genetic study at the sourasky medical center.

Exclusion Criteria

• subjects with cognitive decline by the parameters defined in DSM- IV
• subjects with psychiatric disorder
• subjects unable to sign a consent form

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
healthy relatives	neurological examination	healthy 1st degree relatives of PD patients

Trial Locations

Locations (1)

Tel Aviv Sourasky Medical Center; 🇮🇱 Tel Aviv, Israel