Daily evaluation and spontaneous respiratory test for shorter times in paediatric mechanical ventilatio

Completed

• Conditions: Acute respiratory insufficiency; Respiratory; Postprocedural respiratory disorders, not elsewhere classified

• Registration Number: ISRCTN37806223
• Lead Sponsor: niversity of São Paulo (Brazil)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04-09
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 294

Inclusion Criteria

1. Children aged between 28 days and 15 years old, either sex
2. Admitted to the Hospital das Clínicas da Universidade de São Paulo - HCFMUSP and Hospital Universitário, Brazil, between July 2007 and July 2009
3. Underwent mechanical ventilation for a period over 24 hours

Exclusion Criteria

1. Younger than 28 days
2. Intubation due to upper airway obstruction (UAO)
3. Lack of consent-form
4. Presence of hernia or diaphragmatic paralysis
5. Chronic use of mechanical ventilation
6. Congenital cyanogenic cardiopathy
7. Primary pulmonary hypertension
8. Neuromuscular disease
9. Tracheostomy

Patients were included in the study only once and only the first intubation of those patients requiring a re-intubation was considered in the analysis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of mechanical ventilation compared to weaning, measured at time of extubation

Secondary Outcome Measures

Name	Time	Method
Measured 48 hours after extubation:<br>1. Faulty extubation rate<br>2. Need for post-extubation non-invasive mechanical ventilation