Study to find out Effect of drug esmolol used to prevent raise in blood pressure and heart rate that happens when patient comes out of anaesthesia at the end of laparoscopic surgeries
Phase 3
Completed
- Registration Number
- CTRI/2019/07/020151
- Lead Sponsor
- Kasturba Medical College Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients of either gender,
Aged between 18 to 65 years,
Belonging to ASA-PS I and II,
Undergoing elective laparoscopic surgeries requiring general anaesthesia and endotracheal intubation.
Exclusion Criteria
Patients not giving consent.
Patients with suspected allergy to study drugs (Esmolol).
Patient with difficult airway.
Patients with history of bronchospasm.
Patients with history of bronchial asthma.
Patients with history of cardiovascular diseases
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressureTimepoint: before administering the drug, and after administration, just prior to extubation, then 1 ,2, 3 ,4, 5 minute and at 10 minutes following extubation
- Secondary Outcome Measures
Name Time Method adverse events if any will be recordedTimepoint: post administration of drug/placebo;Quality of Extubation - will be scored on 4 point scale of Eshak (0-No cough or strain, 1-Moderate coughing, 2- High degree of coughing or straining, 3-Poor extubation with laryngospasm). <br/ ><br>Timepoint: post extubation