Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules

Terminated

• Conditions: Thyroid Nodules

• Registration Number: NCT00507897
• Lead Sponsor: Yaroslavl State Medical Academy

Brief Summary

The purpose of this study is to determine the relationship of hemodynamic parameters with the level of thyroid hormones and the histological structure of thyroid nodules in euthyroid patients.

Detailed Description

As opposed to widely investigated condition of cardiovascular system in patients with functional disorders of thyroid gland, the relationship between thyroid hormones and hemodynamic parameters in euthyroid patients remains not enough clear.

We detect the parameters of blood pressure and thyroid hormones in euthyroid patients with thyroid nodules directly before planned operation on the thyroid gland.

As the study is carries out directly before operation, that assumes presence of preoperative stress in patients, activity of the sympatho - adrenal system is estimated in addition.

On the one hand, the design of our research will allow to estimate relationship of thyroid hormones with the parameters of blood pressure in conditions of euthyroidism, on the other hand - to investigate features of blood pressure in patients with thyroid nodules.

The research of the patients in the preoperative period will enable to select the group of patients without pathology of cardiovascular system whose increased blood pressure is connected with preoperative stress, that in turn will allow to exclude influence of the pathology of the cardiovascular system on studied correlation.

Study Timeline

• Study First Submitted: 2007-07-25
• Study First Submitted QC: 2007-07-26
• Study First Posted: 2007-07-27
• Study Completion: 2007-12
• Status Verified: 2008-02
• Last Update Submitted: 2008-02-06
• Last Update Posted: 2008-02-07

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Euthyroid patients with thyroid nodules before operation on the thyroid gland

Exclusion Criteria

• Hyperthyroidism
• Hypothyroidism

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Yaroslavl State Medical Academy; 🇷🇺 Yaroslavl, Russian Federation