The Study of Relationship of Plasma Concentrations of Folic Acid, Vitamin B and Homocysteine With Carotid Atherosclerosis and Endothelium-Dependent Vasodilatation of Geriatric and Young Patients in the Ambulatory Care Department of NTUH

Completed

• Conditions: Homocysteine; Coronary Artery Disease

• Registration Number: NCT00172250
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Elevation of plasma homocysteine has been recognized as one of the risk factors of atherosclerotic disease. The objectives of this study are: (1) to investigate the level of plasma homocysteine and the prevalence of hypehomocysteinemia (2) to find out the role of homocysteine in coronary artery disease and the proper cut-off point of plasma homocysteine to evaluate the presence of coronary artery disease; (3) to understand the control condition of tranditional risk factors of cardiovascular disease, especially hypertension, dyslipidemia, and diabetes mellitus.

The study subjects were recruited from the ambulatory setting of cardiology in National Taiwan University Hospital.

Detailed Description

Not available

Study Timeline

• Study Start: 2003-09
• Status Verified: 2005-08
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-12
• Study First Posted: 2005-09-15
• Last Update Submitted: 2005-11-23
• Last Update Posted: 2005-11-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Patient > 65 y/o or < 50y/o Scr<=1.5mg/dL

Exclusion Criteria

• Scr> 1.5mg/dl pregnancy alcohoism

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified