Homocysteine in Acute Coronary Syndrome

Completed

• Conditions: Acute Coronary Syndrome

• Registration Number: NCT05125419
• Lead Sponsor: Sohag University

Brief Summary

This study aims to determine the relation between high homocysteine levels and increased incidence of acute coronary syndrome in young patients

Detailed Description

Cross sectional study to:

assess homocysteine level in young adult patients presenting with acute coronary syndrome

Study Timeline

• Study First Submitted: 2021-11-06
• Study First Submitted QC: 2021-11-06
• Study First Posted: 2021-11-18
• Study Start: 2021-11-30
• Primary Completion: 2023-05-30
• Status Verified: 2023-07
• Study Completion: 2023-07-01
• Last Update Submitted: 2023-07-04
• Last Update Posted: 2023-07-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. • The patients who presented in the hospital with chest pain consistent with acute coronary syndrome with any of the following features:

   1. Electrocardiogram (ECG) changes:

      • ST elevation
      • ST depression
      • T wave inversion
      • recent left bundle branch block

   2. Troponin T elevation (Norma value < 0.06)

      2- Age: -Between 18- 40 years (Group A) - Age > 40 years (Group B)

Exclusion Criteria

1. Chest pain not consistent with acute coronary syndrome 2. Chronic kidney disease (CKD) 3. Rheumatic heart disease (RHD) 4. Congenital heart disease 5. Anemia 6. Cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Coronary care unit admission with acute coronary syndrome	From date of randomization up to 1 month	Acute coronary syndrome hospitalization and cardiovascular deathes and estimated hazard ratios (HR) by use of multivariable Cox regression models

Trial Locations

Locations (1)

Sohag University; 🇪🇬 Sohag, Egypt