An observational study of serum homocysteine levels , vitamin B12 levels,and prevalence of peripheral neuropathy in patients of Diabetes Mellitus on metformin therapy.
Not Applicable
- Conditions
- Health Condition 1: E114- Type 2 diabetes mellitus with neurological complications
- Registration Number
- CTRI/2024/04/064989
- Lead Sponsor
- Dr Divya Lahoty
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Type 2 DM patients, 18 years and above who fulfilled WHO diagnostic criteria (Blood Sugar Fasting >126 or Blood Sugar >200,2h after glucose challenge) and
2.Patients who are on metformin with or without any other anti-diabetic drugs including insulin.(minimum time duration on metformin therapy 1year)
Exclusion Criteria
1.Has type 1 diabetes mellitus;
2.Has other causes of cobalmine deficiency like malabsorption syndrome or Gastro-Intestinal surgery, alcoholism,etc and
3. Those who have received vitamin supplementation in the last 3 months.
4.Have discontinued metformin in last six months.
5. Any other cause of peripheral neuropathy .
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum homocysteine levels <br/ ><br>Serum vitamin B12 levelsTimepoint: After minimum duration of at least 6 months of metformin therapy
- Secondary Outcome Measures
Name Time Method Prevalence of peripheral neuropathyTimepoint: 1 year