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临床试验/NCT04893070
NCT04893070已完成不适用

Impact of SARS-CoV-2 (COVID-19) Infection, Treated in Ambulatory Care, on Long-term Quality of Life in a Parisian Military Population

Direction Centrale du Service de Santé des Armées1 个研究点 分布在 1 个国家目标入组 173 人开始时间: 2021年7月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
173
试验地点
1
主要终点
Long-term quality of life (mental component)

研究概览

简要总结

In April 2020, a meta-analysis on the long-term sequelae of respiratory syndromes related to seasonal coronaviruses (SARS and MERS) showed a significant alteration in quality of life, with in particular a decrease in physical and emotional capacities and a deterioration of social life. An improvement of the quality of life is evidenced after 6 months but without reaching the level usually observed in healthy people. The impact of SARS-CoV-2 infection on quality of life can be explained by the persistence of pleomorphic symptoms in the medium to long term. In the military population, the majority of SARS-CoV-2 cases present minor to moderate forms of the disease. Military personnel have living conditions that differ from those of the general population, in particular because of their geographic mobility, which may be responsible for isolation from the family. This isolation can be regular (we speak of "geographical celibacy" when the soldier is posted in a geographical area far from the family unit) and/or occasional, during missions on the national territory or outside. This singularity justifies a study on the impact of SARS-CoV-2 (COVID-19) infection on the quality of life in this specific population.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Military personnel
  • COVID+: diagnosed with COVID-19 and managed in ambulatory care since March 14th, 2020
  • COVID-: not having been infected with SARS-CoV-2

排除标准

  • Hospitalized for COVID-19
  • Having received a treatment against COVID-19 (other than paracetamol)

结局指标

主要结局

Long-term quality of life (mental component)

时间窗: 18 months after COVID-19 first symptoms

Mental Component Score (MCS) of the SF-36 questionnaire. The MCS ranges from 0 (bad quality of life) to 100 (good quality of life).

次要结局

  • Long-term quality of life (physical component)(18 months after COVID-19 first symptoms)

研究者

发起方
Direction Centrale du Service de Santé des Armées
申办方类型
Other
责任方
Sponsor

研究点 (1)

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