Comaprison Between QLB and ESPB in Patients for PCNL Operation

Not Applicable

Completed

• Conditions: Pain, Postoperative

• Registration Number: NCT04277611
• Lead Sponsor: Assiut University

Brief Summary

comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.

Detailed Description

Here the investigators are going to compare between the Anterior approach for the subcostal oblique Quadratus Lumborum block (QLB) and the Erector Spinae Plane Block (ESPB) to determine their level of spread and their value in controlling postoperative pain in patients scheduled for Percutaneous Nephrolithotomy surgery. We hypothesized that quadratus lumborum is not inferior regarding the duration of analgesia when compared to erector spinae in patients undergoing percutaneous nephrolithotomy under general anesthesia.

Study Timeline

• Study First Submitted: 2020-02-18
• Study First Submitted QC: 2020-02-19
• Study First Posted: 2020-02-20
• Study Start: 2021-04-20
• Primary Completion: 2022-06-01
• Study Completion: 2022-06-30
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-04
• Last Update Posted: 2022-09-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

• Both sex
• Age: 18-60
• ASA (American Society of Anesthesiologists) class I and II
• Elective surgery
• Patients undergoing PNL surgery

Exclusion Criteria

• Patient's refusal
• Allergy or contraindications to drugs used in the study
• Emergency surgery
• Psychiatric disorders
• Severely co-morbid patients
• Inflammation or infection over injection site
• Bleeding diathesis; INR more than 1.5 and Platelet count less than 100,000/mm3
• Peripheral neuropathy
• Obese patients BMI ≥35
• Patients on previous opioid therapy
• Pre-operative haemoglobin <10 mg/dl
• Inability to properly describe postoperative pain to investigators
• Coagulation abnormalities
• History of drug addiction or alcohol abuse
• History of Previous renal surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Analgesia	48 hours	Total opioid consumption during the first 48hours postoperatively.

Secondary Outcome Measures

Name	Time	Method
time of recovery of bowl movement	5 days postoperative	time from the end of the surgery to the first time of bowl movement
postoperative length of hospital stay	within 2 weeks postoperative.	till time of discharge
Pain Scores using Visual Analog Scale (VAS) Scores	24 hours postoperative.	VAS is a scale to determine the patient's pain level.
ambulation time	5 days postoperative	time from the end of the surgery to the first time to out-of-bed activity
Analgesia	24 hours	first Analgesic request postoperatively.
episodes of nausea and vomiting	within 24 hours postoperative	to investigate if there is or not.
patient satisfaction with anesthesia	48 hours postoperative.	Patient satisfaction with anesthesia was assessed using a 5-point scale (5: very satisfied; 4: satisfied; 3: neither satisfied nor dissatisfied; 2: dissatisfied; 1: very dissatisfied)

Trial Locations

Locations (1)

Assiut University Hospitals; 🇪🇬 Assiut, Egypt