insulin therapy in non-diabetic adults with cystic fibrosis

Completed

• Conditions: cystic fibrosis; 10038686; 10003018

• Registration Number: NL-OMON38361
• Lead Sponsor: HagaZiekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Patients aged 18 years diagnosed with cystic fibrosis, a normal or impaired glucose tolerance test, exocrine pancreatic insufficiency, BMI <21.

Exclusion Criteria

pregnancy, pregnancy wish, lactation, history of organ transplantation, high urgency status on waiting list for transplantation, use of systemic corticosteroids within one month before or during the study period, malignancy, distal intestinal obstruction syndrome (DIOS) or pulmonary exacerbation with hospital admission one month before or during the study period, use of appetite stimulants, BMI >30.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>body weight and body mass index.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Serum pre-albumin/ESR/leucocytes/CRP/vitamin A,D,E,K<br /><br>pulmonary function<br /><br>number of pulmonary exacerbations<br /><br>antibiotic use<br /><br>quality of life<br /><br>foodintake</p><br>