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Comparison of effectiveness among standard dose I-131 plus lithium carbonate, high dose I-131 and high dose I-131 plus lithium carbonate in rapid turnover Graves' disease patients.

Phase 4
Conditions
rapid turnover Graves&#39
disease patients
Registration Number
TCTR20151023001
Lead Sponsor
Ratchapiseksompotch Fund, Faculty of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Enrolling by invitation
Sex
All
Target Recruitment
60
Inclusion Criteria

1.Graves'disease with rapid turnover rate of I-131 uptake (1stRAI)
2. Thyroid gland weight > 50 gm
3. Age over 18 years old

Exclusion Criteria

1.Previous treatment with radioiodine or surgery (total thyroidectomy)
2. Pregnancy or lactation
3. Incomplete course of lithium carbonate

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
percentage of cure 12 months thyroid function test (FT3, FT4, TSH)
Secondary Outcome Measures
NameTimeMethod
none none none
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